Model Number

SKPHAR-07

CAS:127254-12-0

Other name: DU-6859a

DNA topology isomerase ATP hydrolysis inhibitors, DNA topology isomerase IV inhibition

As for the structure of a cis-containing fluoride cyproterone amino corporations, and has a good pharmacokinetic properties, and can reduce adverse reactions, in vitro antibacterial activity than most similar drugs significantly enhanced. The drug is not only significantly improve the gram-positive bacteria of antibacterial activity, but also to many of the separation of fluoroquinolone-resistant strains also have antibacterial activity. On the goods in vitro antibacterial activity of that, with broad-spectrum antibiotic for this role, not only against gram-negative bacteria have antibacterial activity, but also to gram-positive bacteria (methicillin-resistant Staphylococcus aureus, methicillin-resistant grape skin MI), anaerobic bacteria (including fragile Bacteroides) and mycoplasma, chlamydia, and so has strong antibacterial activity, for many common clinical fluoroquinolone-resistant strains also have good sterilization. The drug oral absorption, and the utilization rate of more than 70%, organizations widely distributed, in the central nervous system, a variety of organizations of the drug concentration is higher than the serum concentration, therefore, Ben Pinke looking into the treatment of respiratory tract, genitourinary Road, abdominal and skin and soft tissue, such as single or mixed bacterial infection of important drugs.